Differential Renal Function Studies During Mannitol Diuresis in Hypertension

Differential renal function studies during mannitol diuresis in hypertension.

DIFFERENTIAL renal function studies during water diuresis were introduced by Howard and associates' in 1954 to aid in detection of hypertension secondary to unilateral renal disease. To enhance the diagnostic and prognostic value of such tests, many modifications in the conditions for their performance have been developed: Dustan and co-workers2 studied patients during osmotic diuresis with man...

Changes in renal and urinary kallikrein activity by mannitol-induced osmotic diuresis.

1. Osmotic diuresis was induced in male Sprague-Dawley rats by a 30% (w/v) mannitol solution injected three times at 15-min intervals. Kallikrein excretion increased for a short period after the first two injections, but, despite marked diuresis, the increment of kallikrein excretion after the second injection was less marked than after the first and no enhanced kallikrein excretion was observe...

A Comparative study on Efficacy of 10% and 20% Mannitol for Inducing Diuresis During Renal Transplant Surgery

Objective: Mannitol is one of the most commonly used osmotic diuretics during renal transplant surgery. Two concentrations of mannitol, 10% and 20%, are available, however there is no consensus about which concentration is to be preferred. The purpose of this study was to compare between the efficacy of the two concentrations of mannitol for inducing diuresis during renal transplant surgery and...

Differences between Saline and Mannitol Diuresis in Hydropenic Man.

Free water clearance curves during saline, mannitol, glucose and urea diuresis in the rat.

1. Free water clearances were measured during infusion of hypotonic saline, glucose, urea, and mannitol in Brattleboro rats. For each solute the free water clearances were plotted using either V or (C(H2O) + C(Na)) as the distal tubular delivery term.2. In all cases the use of (C(H2O) + C(Na)) as distal delivery term yielded a steeper relationship than when V was used. There were no significant...